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1. Preheat your oven to 400°F (200°C).
2. In a skillet over medium heat, cook the ground beef and chopped onion until the beef is browned and the onion is tender. Season with salt and pepper. Drain any excess grease.
3. Spread the meat mixture evenly in a 9-inch pie plate.
4. Sprinkle shredded cheddar cheese over the meat mixture.
5. In a medium bowl, whisk together the Bisquick mix, milk, and eggs until well combined. Pour this mixture over the cheese and meat in the pie plate.
6. In a small bowl, mix the ketchup and mustard. Drizzle this over the top of the pie.
7. Bake for about 25 minutes, or until a knife inserted in the center comes out clean.
8. Allow the pie to cool for a few minutes before slicing and serving.
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